5-HTP (5-Hydroxytryptophan is the amino acid that is the intermediate step between tryptophan and serotonin. Tryptophan is an essential amino acid that must be acquired through the consumption of food containing protein, as the body cannot synthesize it. Of the eight essential amino acids, tryptophan is the least common (only about 1 percent of the protein) and is used up rapidly by the body. Approximately 90 percent of the tryptophan available to the body is used in protein synthesis and the other 10 percent is divided between the production of serotonin and niacin. It is felt that modern lifestyles full of stress and the poor dietary habits practiced by many today contribute to lower serotonin levels in the brain. These lowered serotonin levels have been associated with depression, headaches, insomnia, PMS, fibromyalgia, chronic pain, sugar and carbohydrate cravings, and altered moods
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5-HTP has been widely used and studied in Europe since 1970's, and has been available by prescription in the United States for several years.
During this time 5-HTP has been studied widely and its many properties noted. In 1994 5-HTP was introduced as a dietary supplement.

When made in the body, 5-HTP is manufactured in the intestines from the tryptophan the body obtains from protein containing foods.. The supplement form of 5-HTP is extracted from the Griffonia seed. The Griffonia tree is grown primarily in Ghana and the Ivory Coast.

Some research suggests that 5-HTP can be safely used in doses of up to 100 milligrams (mg) per day. It is clear that large excesses of serotonin in the peripheral circulation can cause cardiovascular disease and other adverse effects, so caution should be used to avoid large doses of 5-HTP which could result in the overproduction of serotonin.

COMMON USES OF 5-HTP:

INSOMNIA: In studies with patients suffering from insomnia, 5-HTP was shown to reduce the time required to fall asleep and improved the quality of sleep.

DEPRESSION: Some forms of depression have been attributed to 5-HTP deficiencies. Patients with these forms have shown improvement with 5-HTP supplementation. Clinical trial results have shown 5-HTP and the antidepressants, imipramine and fluvoxamine to have similar effects.

MIGRAINES: Clinical trials showed 5-HTP reduced the frequency and severity of migraines with significantly fewer side effects than prescription drugs.

FIBROMYALGIA: It has been shown that 5-HTP increases serotonin synthesis which increases the body's pain tolerance and sleep quality. Patients with fibromyalgia taking 5-HTP reported improvement in their symptoms of insomnia, depression, anxiety, morning stiffness and the number of painful areas.

OBESITY: 5-HTP creates a feeling of fullness which satisfies a person's appetite sooner. This enables the person to more easily stay on their diet. It has also been shown to decrease the intake of carbohydrates in obese patients.

Many successful studies using 5-HTP have shown that by elevating the serotonin levels in the body 5-HTP can be helpful in dealing with many conditions which seem to result from the depressed serotonin levels. A natural way to deal with many conditions, 5-HTP appears to be the choice of many who do not wish to use prescription drugs.

Supplement Facts
60 Capsules per Bottle
SUGGESTED USE: Take 1 to 2 capsules per day. Usually 1 of our 100 mg capsules is sufficient.

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References:

1. Caniago, C. Ceci, F. Cascino, A. DelBen, M.Laviano, A. Muscaritoli, M. Antonucci, F. Rossin Fanelli, F. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophand, American-jourrnal-of-clinical-nutrition (USA), Nov. 1992, v. 56(5), p. 863-867, 19992,0002-9165.

2. De Beneditis G, Massei R, Serotonin precursors in chronic primary headache. A double-blind corr-over study with L-5-hydroxytryptophan vs. Placebo. J Nemosurg Sci 1985 July-Sep29(3):239-48.

3. Caruso I., Sarzi Puttini P., Cazzola M., Azzolini V., Double-blind study of 5-hydroxytryptophan versus placebo in the treatments of primary fibromyalgia syndrome, J. Int Med Res, 1990 May-Junel8,(3):201-9.

4. Byerley, et al., 5-Hydroxytryptophan: A Review of It's Antidepressant Efficacy and Adverwe Effects. J Clin Psychopharmacol 1987: 7: 127-37.

5. Wurtman, J., Carbohydrate Craving, Mood Changes and Obesity., J Clin Psychiatry., 11988: 49: 37-39.

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