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ALPLR-3010 ALPHA-LIPOIC ACID
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ALPHA-LIPOIC ACID:
THE UNIVERSAL ANTIOXIDANT
Extremely important nutrient
in the
Prevention of a variety of health problems.
• Lipoic Acid and Diabetes
• Lipoic Acid and Cataracts
• Lipoic Acid and HIV
Alpha-Lipoic Acid (ALA)
is a relatively unknown nutrient that has been researched in numerous clinical
and laboratory experiments. First classified as a vitamin, Alpha lipoic acid was
found to be synthesized by both animals and humans, and is now considered to be
an extremely important nutrient in the prevention of a variety of health problems.
Alpha-lipoic acid was
discovered over 50 years ago and
is called the, "Universal Antioxidant"
because it is a potent scavenger of free-radicals in both aqueous and fat soluble
portions of our cells. Lipoic acid not only quenches free-radicals, but can
help to regenerate other antioxidants such as vitamin E, vitamin C and glu-tathione.
Antioxidants work their magic by giving up electrons in order to neutralize
radicals that would otherwise remove them from intact cellular membranes. Lipoic
acid is able to extend the useful life of antioxidants such as those mentioned
above by restoring their missing electrons. Most of this recycling of electrons
is performed by dihy-drolipoic acid, which is formed by the body directly from
lipoic acid .
Lipoic Acid and Diabetes:
ALA has been shown to reduce diabetic neuropathy,
a form of nerve damage associated with a large percentage of diabetics. A large
double-blind study in Germany examined seventy-three adult-onset diabetics who
were randomly assigned to receive several hundred milligrams per day of Alpha-lipoic
acid, or a placebo. After a period of 4 months, the placebo group continued to
show a deterioration in nerve function, compared to a significant improvement
in the patients taking the Alpha-lipoic acid supplements. Alpha-lipoic acid appears
to work in diabetic neuropathy by reducing high levels of oxidative stress at
the cellular level and by activating enzymes that play a key role in the utilization
of glucose.
Lipoic Acid Cataracts
:
Lipoic Acid has been shown to reduce the incidence
of cataracts in a variety of animal studies. These studies suggest that in cases
of diabetes induced cataracts, ALA may prevent oxidative stress in the eye lens
by sparing vitamin C, whose transport is affected by the disease. Lipoic acid
can utilize a lipid transport mechanism and help prevent a localized intracellular
vitamin C deficiency, which is known to a play a key role in the development of
cataracts. Because insulin resistance generally increases with age, ALA has the
potential of protecting more than just those individuals who are currently afflicted
with diabetes.
Lipoic Acid and HIV:
Oxidative stress (free-radical damage), is believed
to play a major role in Human Immunodeficiency Virus or HIV. Some patients with
HIV have been shown to be deficient in a variety of antioxidants. A recent study
examined the use of Lipoic acid supplementation on a group of HIV positive individuals.
At the end of a three week period, patients were determined to have increased
levels of plasma vitamin C and glu-tathione and a corresponding decrease in lipid
peroxidation.
Alpha-Lipoic Acid: More Than
an Antioxidant
There are numerous molecules, known as free radicals,
which cause us to age rapidly and may contribute to serious health problems. Most
of these free radicals, whether they come from pollution, smoke or chemicals,
can be controlled by a group of nutrients called antioxidants. One excellent example
of an antioxidant is Alpha-Lipoic Acid, a substance found in food and manufactured
in small quantities by the body. In 1988, it was discovered that Alpha-Lipoic
Acid was a powerful metabolic antioxidant. When taken within a comprehensive antioxidant
regime, Alpha-Lipoic Acid replenishes Vitamin C and glutathione and helps to recycle
Vitamin E. As an added benefit, Alpha-Lipoic Acid promotes cellular and muscular
energy and functions as a coenzyme in the metabolism of sugars.
Alpha-Lipoic Acid supplementation is necessary whenever increased energy is required;
periods of strenuous physical activity and a desire for optimum vitality are excellent
examples of situations with this need. It is a powerful liver detoxifier and protects
against the effects of toxic metals in the liver. In addition to its effect on
the repair and protection of the liver, Alpha-Lipoic Acid helps to supply energy
to the brain and boosts the effectiveness of the immune system.
As an antioxidant, Alpha-Lipoic Acid is unique
because it is both fat- and water-soluble. Because of this property, it can
enter all areas of the cell affected by free radicals. Alpha-Lipoic Acid also
helps to convert pyruvate into acetyl coenzyme A, one of the main fuels driving
the Krebs Cycle, which provides the body with its energy. As a result, one can
improve the body's rate of metabolism of fats and carbohydrates while increasing
athletic strength and endurance.
When combined with other antioxidants, Alpha-Lipoic
Acid has the ability to lengthen cell life, fight infection, increase energy
and detoxify the body.
Usage:
No serious side effects have been noted in Alpha-lipoic
acid supplementation in either human or animal studies. Suggested dosages run
between 50 and 200 mg per day or as directed. Although the benefits of Alpha-lipoic
acid have been well documented, this marvelous nutrient is just now taking its
place as the "Universal Antioxidant."
Supplement Facts
60 Capsules per Bottle
SUGGESTED USE: Take 1 or 2 capsules per day.
On sale... Order Now! save up to 27%
One Bottle Sale $27.95- Regular $32.95
2 Bottles...$21.95 each - 3 or more Bottles $23.95 each
References:
Nagamatsu, M., et al. " Lipoic acid improves
nerve blood flow, reduces oxidative stress and improves distal nerve conduction
in experimental diabetic neuropathy." Diabetes Care, 18:1160-67, 1995.
Packer, L. et al. "Alpha-lipoic acid as
a biological antioxidant." Free Radical Biology & Medicine, 19:227-250;
1995.
Maitra, I. et al. "Alpha lipoic acid prevents
buthionine sulfoxine-induced cataract formation in rats." Free Radical
Biology & Med., 18: 823-829: 1995.
Note:
These statements have not been evaluated by
the FDA. This information is not intended to diagnose, treat, cure or prevent
any disease. If you have medical problems seek a professional.
Statements on this site have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, prevent, treat, cure or prevent any disease. Please consult a qualified healthcare practitioner for medical advice.
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