DMAE 100 capsules
DMAE may aid in the treatment of ADHD and other disorders affecting the brain and central nervous system.
DMAE, or dimethylaminoethanol,
is a compound found in high levels in anchovies and sardines.
Small amounts of it are also naturally produced in the human brain. Health-food
outlets sell it in capsule form to "boost brain power." It probably
won't make you smarter, but some evidence suggests it may have benefits against
the impulsive and disruptive behaviors caused by attention deficit hyperactivity
disorder (ADHD). It may also have a role in treating memory lapses and Alzheimer's
disease, as well as some troubling movement disorders.
The supplement has an interesting history. Initially,
drug makers were interested in selling the product as a medication for attention
deficit disorder when studies in the 1970s showed that deanol, the chemical name
for DMAE, reduced hyperactivity and improved concentration in schoolchildren with
learning disabilities and behavior problems. However, when further testing was
deemed too expensive, it was packaged as a nutritional supplement, since this
substance is naturally found in fish.
Because it steps up production of brain chemicals essential for short-term memory,
concentration, and learning capacity, DMAE may aid in the treatment of ADHD and
other disorders affecting the brain and central nervous system.
DMAE is sometimes referred to as a "cholinergic" because it is thought
to increase levels of the neurotransmitter acetylcholine, one of the chemicals
in the brain that enhances mental powers. "Cholinergic" drugs, such
as tacrine (Cognex), are used to treat the dementia of Alzheimer's disease.
Cholinergic drugs are also sometimes prescribed to stabilize the debilitating
movements brought on by tardive dyskinesia, a heartbreaking side effect of the
antipsychotic drugs used to treat schizophrenia, and Huntington's chorea, an inherited
condition that also causes memory loss. Researchers have tested DMAE for these
conditions, although results of several small studies have been disappointing.
Still, case reports continue to report some benefits for DMAE in certain individuals
with these movement disorders. Any benefits, if present, may be due to a placebo
effect or some unknown factor that makes certain people particularly responsive
to the supplement.
Marketers have also trumpeted DMAE pills and creams for
everything from prolonging life and enhancing athletic performance to ridding
aging skin of "liver spots." However, there are no sound studies to
support these claims. Moreover, there is no evidence that human beings can suffer
from a deficiency of DMAE.
Specifically, DMAE may help to:
" Relieve the inattention, impulsivity, and hyperactivity of attention deficit
hyperactivity disorder (ADHD). Although ADHD has long been recognized as a cause
of disruptive behavior and learning difficulties in school-age children, doctors
are increasingly coming to recognize it as a cause of problems in adults as well.
Evidence suggests that DMAE may help.
Studies done in children in the 1970s form the basis for DMAE's role in treating
ADHD. One trial assessed 50 hyperactive kids who would likely be diagnosed with
ADHD based on current standards. After 10 weeks, DMAE produced improvements in
behavior compared to a placebo. In another study, children with learning disabilities
were given DMAE, the stimulant Ritalin (methylphenidate, the most commonly prescribed
drug for ADHD), or a dummy pill. Those who were given either DMAE or Ritalin showed
objective improvements on concentration and skills tests.
Some recent research points to deficits in short-term, or working, memory in both
children and adults with ADHD (although long-term memory is fine in these patients).
Some of DMAE's possible benefits for ADHD may therefore be due to its memory-boosting
potential. Studies have yet to confirm this effect, however.
" Slow the progressive dementia of Alzheimer's disease. The severe and progressive
memory loss of Alzheimer's disease is due in part to the loss of brain cells that
produce acetylcholine, a key chemical messenger for enhancing communication between
brain cells. Acetylcholine is also essential for learning and memory. In fact,
it's for these reasons that doctors routinely prescribe drugs that boost levels
of acetylcholine, such as tacrine (Cognex), donepezil (Aricept), rivasatigmine
(Exelon), and galantamine (Reminyl).
In animal studies, DMAE supplements have led to significant improvements in short-term
memory, possibly due to cholinergic effects. A number of small studies indicate
that DMAE may have similar benefits for people with Alzheimer's.
Not all studies have been positive, however. In one trial, when researchers compared
DMAE to a placebo in 27 Alzheimer's patients, the DMAE supplements provided no
benefit. In fact, nearly half of the patients stopped taking DMAE due to unpleasant
side effects such as drowsiness and increased confusion. Other research investigating
whether DMAE is truly a precursor of acetylcholine has been mixed as well, calling
into question the supplement's effectiveness for Alzheimer's and other memory
Improve memory. The possible memory-boosting effects
of DMAE may help with the ordinary memory lapses that occur with normal aging.
Many nutritionally oriented physicians prescribe DMAE along with another memory
enhancer, the dietary supplement phosphatidylcholine. Although rigorous studies
are lacking, some people who have tried DMAE report better memory (especially short-term memory), as well as improved concentration, focus, mental clarity,
100 Capsules per Bottle
SUGGESTED USE: As a dietary supplement take 1 to 2 capsules per day with water or juice.
On sale... Order Now! save up to 48%
One Bottle Sale $15.95- Regular
3 or more Bottles $12.95 each
Statements on this site have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, prevent, treat, cure or prevent any disease. Please consult a qualified healthcare practitioner for medical advice.
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